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      名:

高兴华

      称:

副研究员

出生年月:

1984.03

办公地点:

宝山校区7号楼523/嘉定校区化学楼421

电子邮箱:

Gaoxinghua@t.shu.edu.cn

个人简况

工作经历:

2019-03     至 今, 上海大学, 材料基因组工程研究院, 副研究员

2015-07     2019-03, 上海大学,     材料基因组工程研究院, 助理研究员

2013-07     2015-07, 深圳北京大学香港科技大学医学中心,博士后

 

教育经历:

2006-09     2013-01, 中国科学院大连化学物理研究所, 分析化学, 博士

2002-09     2006-07, 兰州大学,     化学, 学士

研究方向

主要从事基于微流控芯片技术的器官芯片构建、生物材料合成等应用基础研究,集中关注胰岛、肺、脑及相关肿瘤组织等生理病理微环境的体外构建与模拟。现担任全国生物样本标准化技术委员会(SAC/TC559)委员、中国生物工程学会器官芯片与微生理系统分会委员,在相关研究领域获得国家自然科学基金青年基金一项,省自然科学基金一项,参与国家自然科学基金重点项目和科技部国家重点研发计划等,累计发表SCI论文40余篇,包括BiomaterialsMaterials Today BioAdvanced Healthcare MaterialsFood Research InternationalLab on a chip等期刊。

具体研究方向:

Ø 生物微流体技术

Ø 器官芯片、微生理系统

Ø 生物材料、三维打印


代表性成果

[1] J. Shi, J. Li, J. Ma, X. Yang, C. Xue, Y. Zhang and X. Gao *, Engineering pancreatic islet-loaded microfibers via pneumatically-controlled microfluidic spinning for the assembly of a microphysiological system, Biomaterials, 2026, 324, 123480

[2] J. Li, X. Gao *, X. Yang, H. Wang, X. Sun, C. Xue, J. Ma*. Engineering spatially defined extracellular matrix gradients to govern self-organized multicellular aggregates in a glioblastoma-on-a-chip. Lab on a chip, 2026, 26, 178–192

[3] X. Yang, J. Shi, B. Shi, J. Li, C. Xue, J. Ma * and X. Gao *, Micro- and nano-fibers for organ-on-a-chip: Construction, applications, and prospects. Materials Today Bio, 2024, 29, 101322

[4] L. Tian, J. Shi, W. Li, Y. Zhang and X. Gao *, Hollow Microfiber Assembly-Based Endocrine Pancreas-on-a-Chip for Sugar Substitute Evaluation, Advanced Healthcare Materials, 2024, 13, 2302104

[5] J. Shi; J. Li; W. Su *; C. Xue; Y. Zhang and X. Gao *, Engineered microenvironments and pancreatic islet-on-chips for screening sugar substitute and antidiabetic compounds. Food Research International, 2024, 196, 115084

[6] J. Ma *, W. Li, L. Tian and X. Gao *, Preparation of tunable hollow composite microfibers assisted by microfluidic spinning and its application in the construction of in vitro neural models, International Journal of Bioprinting, 2024, 10(2), 264-278

[7] J. Tan, L. Zhu, J. Shi, J. Zhang., J. Kuang, Q. Guo, X. Zhu, Y. Chen, C. Zhou * and X. Gao *, Evaluation of drug resistance for EGFR-TKIs in lung cancer via multicellular lung-on-a-chip, European Journal of Pharmaceutical Sciences, 2024, 199, 106805

[8] Z. Mao, B. Shi, J.Wu and X. Gao *, Mechanically mediated cargo delivery to cells using microfluidic devices, Biomicrofluidics, 2024, 18, 061302

[9] L. Tian, J. Ma, W. Li, X. Zhang * and X. Gao *, Microfiber Fabricated via Microfluidic Spinning toward Tissue Engineering Applications, Macromolecular Bioscience, 2023, 23(3), 2200429

[10] X. Sun, Q. Wu, W. Li, X. Gong, J. Ge, J. Wu * and Gao X. *, Facile fabrication of drug-loaded PEGDA microcapsules for drug evaluation using droplet-based microchip. Chinese Chemical Letters, 2022, 33 (5): 2697-2700


 

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